abstract：:This systematic review was designed to find out optimal tacrolimus dose in pediatrics according to their CYP3A5*1 genotype by performing meta-analysis. PubMed, Scopus, ISI web of Science, ProQuest, Cochrane library, and clinicaltrail.gov were systematically searched to find studies in which tacrolimus dose and/or bloo...

journal_title：Pediatric transplantation

authors： Hendijani F,Azarpira N,Kaviani M

更新日期：2018-06-19 00:00:00

abstract：:ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of CDV as a potential therapeutic agent. We present the findings of our retrospective study evaluating the effic...

journal_title：Pediatric transplantation

authors： Guerra Sanchez CH,Lorica CD,Arheart KL,Perez MM,Tekin A,Gonzalez IA

更新日期：2018-06-03 00:00:00

abstract：:Anemia is a well-described comorbidity in patients with heart failure and has been associated with decreased survival rates after heart transplant. The causes of anemia are broad, and identification of the underlying etiology is critical for management. Herein, we report an unusual case of severe anemia complicating c...

journal_title：Pediatric transplantation

authors： Lehto E,Raj A,Sparks J

更新日期：2018-06-01 00:00:00

abstract：:Although TEG directs effective resuscitation in adult surgical patients, pediatric data are lacking. We performed a retrospective comparative review of the effect of TEG on blood product utilization and outcomes following pediatric liver transplantation in 38 patients between 2008 and 2014. Diagnoses, laboratory value...

journal_title：Pediatric transplantation

authors： Sujka J,Gonzalez KW,Curiel KL,Daniel J,Fischer RT,Andrews WS,Wicklund BM,Hendrickson RJ

更新日期：2018-06-01 00:00:00

abstract：:There is currently no way to diagnose a rejection before a change in serum creatinine. This had led some to start doing SB, but little data exist on the utility and safety of SB in pediatric patients. There is also little known on practice patterns of pediatric nephrologists. A retrospective review of pediatric kidney...

journal_title：Pediatric transplantation

authors： Nazario M,Nicoara O,Becton L,Self S,Hill J,Mack E,Evans M,Twombley K

更新日期：2018-06-01 00:00:00

abstract：:Many pediatric centers utilize a variety of protocols including preemptive plasmapheresis to prevent the recurrence of FSGS post-transplant. But the effectiveness of this expensive, time-consuming process of plasmapheresis in the prevention of FSGS recurrence is still unclear. We retrospectively reviewed all pediatric...

journal_title：Pediatric transplantation

authors： Verghese PS,Rheault MN,Jackson S,Matas AJ,Chinnakotla S,Chavers B

更新日期：2018-05-01 00:00:00

abstract：:This study reports the clinical complication and infection rates of an active pediatric IT program that has never utilized bowel decontamination in either the donor or the recipient. All patients undergoing IT from 2003 to 2015 at a single pediatric IT center were reviewed. Post-transplant surgical, infectious, and im...

journal_title：Pediatric transplantation

authors： Clouse JW,Kubal CA,Fridell JA,Mangus RS

更新日期：2018-05-01 00:00:00

abstract：:Maintaining fluid balance, pre- and post-MA-HCT is essential and usually requires frequent administration of diuretics. Hepatic sinusoidal obstructive syndrome is potentially life-threatening, especially when associated with AKI and MOF. This study describes six patients who developed AKI-associated SOS and diuretic-r...

journal_title：Pediatric transplantation

authors： Raina R,Abusin GA,Vijayaraghavan P,Auletta JJ,Cabral L,Hashem H,Vogt BA,Cooke KR,Abu-Arja RF

更新日期：2018-03-01 00:00:00

abstract：:Across pediatric organ transplant populations, patient and family psychosocial functioning is associated with important health-related outcomes. Research has suggested that pediatric heart transplant recipients and their families are at increased risk for adverse psychosocial outcomes; however, recent investigation of...

journal_title：Pediatric transplantation

authors： Cousino MK,Schumacher KR,Rea KE,Eder S,Zamberlan M,Jordan J,Fredericks EM

更新日期：2018-03-01 00:00:00

abstract：:Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopat...

journal_title：Pediatric transplantation

authors： Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

更新日期：2018-03-01 00:00:00

abstract：:Infants listed for heart transplantation experience high waitlist and early post-transplant mortality, and thus, optimal allocation of scarce donor organs is required. Unfortunately, the creation and validation of multivariable regression models to identify risk factors and generate individual-level predictions are ch...

journal_title：Pediatric transplantation

authors： Chen CK,Manlhiot C,Mital S,Schwartz SM,Van Arsdell GS,Caldarone C,McCrindle BW,Dipchand AI

更新日期：2018-03-01 00:00:00

abstract：:Non-adherence to immunosuppressant medications is an important risk factor for graft dysfunction. To evaluate the effectiveness of adherence-enhancing interventions, we reviewed adherence intervention studies in solid organ transplant recipients (all ages). Using the following databases: PsycINFO, PubMed, Scopus, and ...

journal_title：Pediatric transplantation

authors： Duncan S,Annunziato RA,Dunphy C,LaPointe Rudow D,Shneider BL,Shemesh E

更新日期：2018-02-01 00:00:00

abstract：:Anelloviruses are DNA viruses ubiquitously present in human blood. Due to their elevated levels in immunosuppressed patients, anellovirus levels have been proposed as a marker of immune status. We hypothesized that low anellovirus levels, reflecting relative immunocompetence, would be associated with adverse outcomes ...

journal_title：Pediatric transplantation

authors： Blatter JA,Sweet SC,Conrad C,Danziger-Isakov LA,Faro A,Goldfarb SB,Hayes D Jr,Melicoff E,Schecter M,Storch G,Visner GA,Williams NM,Wang D

更新日期：2018-02-01 00:00:00

abstract：:The outcomes of pediatric ventricular assist device support in patients with diastolic heart failure have not been well described. This study reviews the North American experience with Berlin Heart EXCOR® ventricular assist device implants in children with such physiology. The Berlin Heart clinical database was review...

journal_title：Pediatric transplantation

authors： Su JA,Menteer J

更新日期：2017-12-01 00:00:00

abstract：:CHS is a rare immunodeficiency syndrome with defects in the functions of cytotoxic cells and neutrophils. Approximately 85% of patients with CHS undergo an AP within the first decade, which is similar to FHLH. Chemotherapy could induce transient remission, but only allogeneic HCT could correct the underlying genetic d...

journal_title：Pediatric transplantation

authors： Zhang Y,Gao Z,Yu X

更新日期：2017-11-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9-year-old girl, remote from transplant, who presented with airway plaque after a change in immunosuppres...

journal_title：Pediatric transplantation

authors： Ryan TD,Absalon MJ,de Alarcon A,Gupta A,Peters AL,Lorts A,Danziger-Isakov LA,Chin C

更新日期：2017-11-01 00:00:00

abstract：:Facial transplantation has become a reality in adult medicine. Children are subject to congenital craniofacial differences, disease-related, traumatic, or thermochemical craniofacial changes and might be suitable for face transplantation. This manuscript addresses unique ethical issues in considering potential pediatr...

journal_title：Pediatric transplantation

authors： Benghiac AG,Garrett JR,Carter BS

更新日期：2017-11-01 00:00:00

abstract：:Little has been studied regarding the diets of children following LTX. The study aim was to assess and compare dietary intake and DQ of healthy children and children post-LTX. Children and adolescents (2-18 years) post-LTX (n=27) and healthy children (n=28) were studied. Anthropometric and demographic data and two 24-...

journal_title：Pediatric transplantation

authors： Alzaben AS,MacDonald K,Robert C,Haqq A,Gilmour SM,Yap J,Mager DR

更新日期：2017-09-01 00:00:00

abstract：:Secondary failure of platelet engraftment occurs in 20% of patients undergoing allogeneic HSCT and is associated with poor outcome. Currently, there are no guidelines for treatment of late thrombocytopenia and platelet transfusion is the mainstay of treatment. Here, we describe the use of Eltrombopag to treat secondar...

journal_title：Pediatric transplantation

authors： Ali S,Gassas A,Kirby-Allen M,Krueger J,Ali M,Schechter T

更新日期：2017-09-01 00:00:00

abstract：:Drowning, a common cause of death in the pediatric population, is a potentially large donor pool for OLT. Anecdotally, transplant centers have deemed these organs high risk over concerns for infection and graft dysfunction. We theorized drowned donor liver allografts do not portend worse outcomes and therefore should ...

journal_title：Pediatric transplantation

authors： Kumm KR,Galván NTN,Koohmaraie S,Rana A,Kueht M,Baugh K,Hao L,Yoeli D,Cotton R,O'Mahony CA,Goss JA

更新日期：2017-09-01 00:00:00

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:Few studies have identified the psychosocial characteristics of those children and their families associated with future non-adherence to immunosuppressive medications following a heart or lung transplant. UNOS data and medical records information were used to test the association between patient and family psychosoci...

journal_title：Pediatric transplantation

authors： Killian MO

更新日期：2017-06-01 00:00:00

abstract：:Dyslipidemia contributes to cardiovascular morbidity and mortality in pediatric transplant recipients. Data on prevalence and risk factors in pediatric cohorts are, however, scarce. We therefore determined the prevalence of dyslipidemia in 386 pediatric renal transplant recipients enrolled in the CERTAIN registry. Dat...

journal_title：Pediatric transplantation

authors： Habbig S,Volland R,Krupka K,Querfeld U,Dello Strologo L,Noyan A,Yalcinkaya F,Topaloglu R,Webb NJ,Kemper MJ,Pape L,Bald M,Kranz B,Taylan C,Höcker B,Tönshoff B,Weber LT

更新日期：2017-05-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:Renal transplantation is the therapy of choice in children with ESKD. Radiological investigations are required in both pre- and post-transplant assessment, although there is paucity of both consensus-based statements and evidence-based imaging guidelines in pediatric renal transplantation. The phases of pediatric ESKD...

journal_title：Pediatric transplantation

authors： Damasio MB,Ording Muller LS,Piaggio G,Marks SD,Riccabona M

更新日期：2017-05-01 00:00:00

abstract：:To evaluate social development of pediatric heart transplant (tx) recipients who have lived 15 or more years after transplantation. Among 498 pediatric patients, age less than 18 years, who underwent heart transplantation, at a single institution, 337 were performed between 1985 and 1998. We identified all who survive...

journal_title：Pediatric transplantation

authors： Copeland H,Razzouk A,Beckham A,Chinnock R,Hasaniya N,Bailey L

更新日期：2017-03-01 00:00:00

abstract：:Early graft loss and poor graft function limit the use of kidneys from infant donors. Six en bloc kidney transplantations were performed from infant donors younger than 10 months into pediatric recipients between November 2012 and September 2015 at our center. We retrospectively analyzed recipient and donor demographi...

journal_title：Pediatric transplantation

authors： Wang HY,Li J,Liu LS,Deng RH,Fu Q,Ko DS,Zhang HX,Deng SX,Wang CX

更新日期：2017-03-01 00:00:00

abstract：:Predictors of successful transition from pediatric to adult services include ability to self-manage and engage with healthcare services. Parents have a key role in healthcare management throughout childhood and adolescence including encouraging development of self-management skills in their children. Transition to adu...

journal_title：Pediatric transplantation

authors： Wright J,Elwell L,McDonagh JE,Kelly DA,Wray J

更新日期：2017-02-01 00:00:00

abstract：:CGD is a rare primary immunodeficiency with high mortality rates when treated conventionally, especially for the X-chromosome-linked form. HSCT is the only curative therapy for CGD; however, haploidentical transplantation in CGD is rare. Here, we report a case of X-linked CGD treated successfully by haploidentical HSC...

journal_title：Pediatric transplantation

authors： Zhou L,Dong LJ,Gao ZY,Yu XJ,Lu DP

更新日期：2017-02-01 00:00:00

abstract：:Vaccination of pediatric liver transplant candidates and recipients represents an opportunity to decrease infectious complications following transplant. Although vaccine recommendations exist, studies have shown that many transplant candidates and recipients are under-immunized. The goals of this study were to assess ...

journal_title：Pediatric transplantation

authors： Feldman AG,Kempe A,Beaty BL,Sundaram SS,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2016-12-01 00:00:00

abstract：:Adults, older children, and adolescent patients with a BMI categorized as overweight or obese have decreased survival after HTx. Anthropometric correlates of survival after HTx in infants have not been well defined. In a retrospective analysis of the UNOS registry, patients age 0-24 months were classified according to...

journal_title：Pediatric transplantation

authors： McKee C,Tumin D,Hayes D Jr,Tobias JD

更新日期：2016-12-01 00:00:00

abstract：:Liver transplant is a treatment option for patients with MMA-emia. While this therapy does not bring about a complete cure, it is expected to prolong survival and improve the QOL of patients. The aim of this study was to evaluate the significance of LDLT for patients with MMA-emia in Japan. Clinical information on 13 ...

journal_title：Pediatric transplantation

authors： Sakamoto R,Nakamura K,Kido J,Matsumoto S,Mitsubuchi H,Inomata Y,Endo F

更新日期：2016-12-01 00:00:00

abstract：:We sought to examine the relationship between liver transplant-related total cost, patient outcome, and hospital resource utilization at freestanding children's hospitals. Using the PHIS database, a retrospective study of 374 patients that underwent liver transplantation at 15 freestanding children's hospitals from Ju...

journal_title：Pediatric transplantation

authors： Minneman JA,Grijalva JL,LaQuaglia MJ,Kim HB,Rangel SJ,Vakili K

更新日期：2016-11-01 00:00:00

abstract：:Germline GATA2 mutations have been associated with a vast array of clinical manifestations, as well as hematological deficiencies and a propensity to AML or MDS. We present two cases of pediatric AML/MDS with underlying GATA2 mutations who underwent a successful umbilical cord hematopoietic stem cell transplantation u...

journal_title：Pediatric transplantation

authors： Mallhi K,Dix DB,Niederhoffer KY,Armstrong L,Rozmus J

更新日期：2016-11-01 00:00:00

abstract：:IMN contribute to ESRD in 13% children with renal transplant (txp). Recurrent or de novo IMN can cause graft dysfunction and/or failure, but the details regarding incidence, therapy, and outcome remain poorly understood. Retrospective single-center study of all pediatric kidney txp was carried out since 1998. Clinical...

journal_title：Pediatric transplantation

authors： Roberti I,Vyas S

更新日期：2016-11-01 00:00:00

abstract：:Organ transplant is life-saving and any given organ may be valuable to a multitude of potential recipients. An allocation system must be used to reconcile the difference between supply and demand, and this system must take into account the impact that accepting international patients may have on the local system. The ...

journal_title：Pediatric transplantation

authors： Lorts A,Ryan TD,Matheny Antommaria AH,Lake M,Bucuvalas J

更新日期：2016-09-01 00:00:00

abstract：:LT is an effective therapeutic option for a variety of IEM. This approach can significantly improve the quality of life of patients who suffer from severe disease manifestations and/or life-threatening metabolic decompensations despite medical/dietary management. Due to the significant risks for systemic complications...

journal_title：Pediatric transplantation

authors： Oishi K,Arnon R,Wasserstein MP,Diaz GA

更新日期：2016-09-01 00:00:00

abstract：:There are few reports on the clinical significance of MRD before HSCT in pediatric ALL. We retrospectively analyzed the clinical significance of FCM-based detection of MRD (FCM-MRD) before allogeneic HSCT in pediatric ALL. Of 38 pediatric patients who underwent allogeneic HSCT for the first time between 1998 and 2014,...

journal_title：Pediatric transplantation

authors： Umeda K,Hiramatsu H,Kawaguchi K,Iwai A,Mikami M,Nodomi S,Saida S,Heike T,Ohomori K,Adachi S

更新日期：2016-08-01 00:00:00

abstract：:Activation of the RAS has a crucial role in the progression of ischemia/reperfusion-associated CAD. The regulation of RAS differs in the two genders. However, the extent of gender differences and locations of renin production have not been revealed yet. We investigated in vivo the local renin production in the two gen...

journal_title：Pediatric transplantation

authors： Csohány R,Prókai Á,Sziksz E,Balicza-Himer L,Pap D,Kosik A,Sugár D,Vannay Á,Kis-Petik K,Fekete A,Szabó AJ

更新日期：2016-08-01 00:00:00